Treatment
Profhilo Structura
Structural bioremodeling of the mid-face — the next generation of HA stabilisation.
Duration
Up to 6 months
Results visible
After 4–8 weeks
Maintenance
2 sessions, then every 6 months
Price
from 499 EUR
Profhilo Structura is not "Profhilo 2.0" — it is a distinct concept. While classic Profhilo stimulates skin quality at the cellular level, Structura targets a different layer: the fat compartments and structural support of the mid-face region. The result is not classical volume filling — it is bioremodeling of the structures that hold the mid-face.
Medically reviewed by Dr. Felicitas Mrochen — Last updated: April 2026
Your Benefits
- Structural bioremodeling of the mid-face region
- Addresses declining fat compartments from age 40+
- Patented HMW + LMW hyaluronic acid combination
- Only 2 sessions, 4 weeks apart
- Effect up to 6 months, with build-up effect on follow-up appointments
- Subtle, natural lift without classic filler appearance
How the procedure works
1
Mid-face analysis: assessment of fat compartments, skin quality, individual anatomy.
2
Preparation: skin cleansing, optional numbing cream.
3
Injection session 1: Structura is placed deep, in the structural layers of the cheeks.
4
Distribution phase: the product integrates into the tissue over 2–4 weeks.
5
Session 2 after 4 weeks: completion of protocol for stable result.
6
Follow-up after 8–12 weeks: progress assessment, potential recommendation for additional building blocks.
HMW + LMW: what the combination achieves
Structura combines high- and low-molecular hyaluronic acid in a stabilised complex. The high-molecular fraction provides structural stability, the low-molecular fraction addresses the tissue micro-environment. The result is a different material profile than classic Profhilo — firmer, deeper acting.
Mid-face: why this region matters
The mid-face carries central perceptual cues: cheek height, transition to jawline, supportive function for the lower face. When fat compartments soften here, the face appears tired — even with otherwise good skin quality. Structura targets exactly this structural level.
What Structura is not
Structura does not replace classic cheek-augmentation with cross-linked hyaluronic acid when significant volume is the goal. It is the choice for patients seeking structural support — without the classic filler look.
Frequently Asked Questions
What distinguishes Structura from classic Profhilo?
Classic Profhilo hydrates skin and stimulates collagen. Structura addresses deeper structural levels and fat compartments. The application area is the mid-face, not facial-wide.
For which age is Profhilo Structura suitable?
In practice, Structura is most useful from age 40+. Mid-face fat compartments begin losing volume and firmness then. Younger patients usually benefit more from classic Profhilo.
Is this a filler?
In the strict sense, no. Fillers add volume at a point. Structura works through bioremodeling of existing structures. Tissue is supported, not padded.
How long does the result last?
Clinical data show an effect window of up to six months. With repeated application at six-month rhythm, structural support builds up.
Can I combine Structura with other treatments?
Yes. Common combinations include classic Profhilo for skin quality and targeted hyaluronic acid treatment for cheeks or jawline. The sequence is discussed individually.
What does a Profhilo Structura treatment cost?
A session starts from 499 EUR. The full protocol involves two sessions, four weeks apart.
Interested in Profhilo Structura?
In a personal consultation, we discuss your wishes and find the optimal treatment for you.
Book a consultationScientific Evidence
- [1] Cassuto D et al.. Profhilo Structura: Pilot Evaluation in Mid-Face Volume Restoration. J Cosmet Dermatol (2024).
- [2] Cassuto D, Bellia G. Stabilized Hybrid Cooperative Hyaluronic Acid Complexes — Mid-Face Indications. Aesthet Surg J (2023).
Linked studies serve as scientific context and do not constitute treatment guarantees.
